While anything is possible, I don't understand why you'd want to keep the shock towers. It's one of the weakest links of the entire car and is 50 year old suspension technology.
Install a modern motor and keep a POS front suspension? Why?
Here's a couple file photos I have of mod motors.
The first shows the size difference between a SBF and a 4.6 4V.....
This photo shows a 5.4 in a 65-66....
Lastly, a '67 getting prepped for a 4.6 install....
